Morphometric evidence that epithelial basement membrane breaks are a feature of both squamous and basal cell carcinomas of the skin
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چکیده
منابع مشابه
Expression of basement membrane laminin in oral squamous cell carcinomas.
UNLABELLED The basement membrane is a dynamic structure that undergoes quantitative and qualitative changes during the progression of squamous cell carcinoma, which is essentially important in tumoral invasion and metastasis. AIM This study is aimed at investigating the behavior of the basement membrane in oral squamous cell carcinomas with different malignancy scores, which were obtained thr...
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Background: In addition to the well-defined histological criteria for squamous cell carcinoma (SCC) and basal cell carcinoma (BCC), immunohistochemical techniques can be used in difficult cases for their differentiation. As differential diagnosis between trichoepithelioma (TE) and BCC is sometimes difficult for the clinician and the pathologist, CD10 may be a useful marker for definite diagnosi...
متن کاملImmunohistochemical expression of CD10 in cutaneous basal and squamous cell carcinomas
Background: Non-melanoma skin cancer is the most common malignant tumor in humans. The role of ultraviolet radiation is well-known in the pathogenesis of basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). CD10 is a zinc-dependent metallopeptidase known as common acute lymphoblastic leukemia antigen (CALLA). Although CD10 expression has been investigated in some cutaneous tu...
متن کاملBasal cell carcinomas and squamous cell carcinomas of human skin show distinct patterns of chromosome loss.
Although basal cell carcinomas and squamous cell carcinomas are clinically and pathologically distinct, the molecular basis for these differences is not clear. We have used polymorphic microsatellite markers to determine the pattern and extent of chromosome losses in a series of 44 basal cell carcinomas and 47 squamous cell neoplasms of the skin. Basal cell carcinomas showed a distinctive allel...
متن کاملBasal Cell Carcinomas and Squamous Cell Carcinomas of Human Skin Show Distinct Patterns of Chromosome Loss1
Although basal cell carcinomas and squamous cell carcinomas are clinically and pathologically distinct, the molecular basis for these differ ences is not clear. We have used polymorphic microsatellite markers to determine the pattern and extent of chromosome losses in a series of 44 basal cell carcinomas and 47 squamous cell neoplasms of the skin. Basal cell carcinomas showed a distinctive alle...
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ژورنال
عنوان ژورنال: International Journal of Cancer
سال: 1996
ISSN: 0020-7136,1097-0215
DOI: 10.1002/(sici)1097-0215(19960328)66:1<24::aid-ijc5>3.3.co;2-5